YenzoWhat is E1101 (protease, papain and bromelain)?
E1101 covers protease, papain and bromelain. In Appendix 1 of Circular 24/2019/TT-BYT the functions listed for them are flavour enhancer, flour treatment agent, stabilizer.
E1101Protease, invertase and papain
E1101 covers protease, papain and bromelain (INS 1101). In Circular 24/2019/TT-BYT they are listed in Appendix 1 with the functions: flavour enhancer, flour treatment agent, stabilizer.
- Code
- E1101 · INS 1101
In Vietnam✓ PermittedOn the list of permitted additives — Circular 24/2019, Appendix 1
Risk level on the Yenzo Scalevery low?Based on the Open Food Facts additives taxonomy
How E1101 appears on labels
IngredientsIllustrative example
Wheat flour, vegetable oil, salt, sugar, flour treatment agent (1101), dried onion and garlic, pepper, natural colour (160a).
flour treatment agent (1101)flour treatment agent 1101E1101INS 1101
INS sub-codes
INS 1101(i)Protease
INS 1101(ii)Papain
INS 1101(iii)Bromelain
INS 1101(iv)Ficin
Sources: Codex CXG 36-1989, Class Names and the International Numbering System (INS)
Questions about protease, invertase and papain
Is the protease, papain and bromelain group harmful?
The JECFA database (the FAO/WHO expert committee) records each substance of this group separately. Protease from Aspergillus oryzae (INS 1101i) has an ADI of “not specified” (no numerical ADI is needed), evaluated in 1987. Papain (INS 1101ii) and bromelain (INS 1101iii) have an ADI of “not limited”, evaluated in 1971, with the comment that use is limited by good manufacturing practice (GMP). These are JECFA evaluations, not EFSA opinions or the current EU rule.
Is E1101 permitted in Vietnam?
Yes. Protease, papain and bromelain (INS 1101(i), 1101(ii), 1101(iii)) is listed in Appendix 1 of Circular 24/2019/TT-BYT, the list of additives permitted in food.
Other flour treatment agents
E920L-Cysteinevery lowE924Bromates (flour treatment agent)highE924aPotassium bromatehighE927bCarbamide (urea)lowE1100Amylasevery lowE1421Starch acetate esterified with vinyl acetatevery low
See all flour treatment agents →Found in these products
Updated 23 October 2026
Sources (5)
- Open Food Facts additives taxonomy (Yenzo's table cites no EFSA opinion for this code). Open Food Facts additives taxonomy, https://github.com/openfoodfacts/openfoodfacts-server/blob/main/taxonomies/additives.txt (entry en:e1101)
- Thông tư 24/2019/TT-BYT (văn bản hợp nhất 09/VBHN-BYT), Phụ lục 1
- JECFA (FAO/WHO) evaluation database: Protease from Aspergillus oryzae, INS 1101i, evaluation 1987
- JECFA (FAO/WHO) evaluation database: Papain, INS 1101ii, evaluation 1971
- JECFA (FAO/WHO) evaluation database: Bromelain, INS 1101iii, evaluation 1971