E539Sodium thiosulphate

E539 is sodium thiosulfate (natri thiosulfat). In Appendix 1 of Circular 24/2019/TT-BYT it is listed with the functions: antioxidant, sequestrant.

Code: E539 · INS 539
Group: Antioxidant, Sequestrant
ADI: 0-0.7 mg/kg bw (JECFA 1998 (group ADI, expressed as sulfur dioxide))

In Vietnam✓ PermittedOn the list of permitted additives — Circular 24/2019, Appendix 1

Risk level on the Yenzo Scalemoderate?Based on the Open Food Facts additives taxonomy

How E539 appears on labels

IngredientsIllustrative example

Wheat flour, vegetable oil, salt, sugar, antioxidant (539), dried onion and garlic, pepper, natural colour (160a).

antioxidant (539)antioxidant 539E539INS 539On Vietnamese labels: Natri thiosulfat

Questions about sodium thiosulphate

What is E539 (sodium thiosulfate)?

Circular 24/2019/TT-BYT (Appendix 1) lists INS 539 with the functions: antioxidant, sequestrant.

Is sodium thiosulfate harmful?

JECFA (the joint FAO/WHO expert committee on food additives) evaluated sodium thiosulfate (INS 539) in 1998 together with the sulphites and set a group ADI of 0-0.7 mg/kg body weight, expressed as sulfur dioxide. In the United States, 21 CFR 184.1807 lists sodium thiosulfate as used as a formulation aid and a reducing agent.

Is sodium thiosulfate permitted in Vietnam?

Yes. Sodium thiosulfate (INS 539) is listed in Appendix 1 of Circular 24/2019/TT-BYT, the list of additives permitted in food.

Other antioxidants

E385Calcium disodium EDTAlow E386Disodium EDTAlow E392Extracts of rosemaryvery low E472Esters of mono- and diglycerides of fatty acidslow E512Stannous chloridelow E5864-Hexylresorcinollow

See all antioxidants →

Updated 23 October 2026

How Yenzo scores

Sources (4)

Information only, not medical advice. The risk level is the additive's class in Yenzo's open scoring method, based on the cited source.